Journal article
Interferon lambdas: the next cytokine storm
- Abstract:
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For two decades the scientific community has sought to understnad why some people clear hepatitis C virus (HCV) and others do not. Recently, several large genome-wide association studies have identified single nucleotide polymorphisms (SNPs) linked to interferon lambda 3 (IFNλ3) that are associated with the spontaneous resolution and successful treatment of HCV infection. These observations are generating intense research activity; the hope is that IFNλ3 genetic variants may serve as importan...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 280.3KB)
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- Publisher copy:
- 10.1136/gut.2010.222976
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Authors
Funding
+ "Oxford NIHR Biomedical Research Centre", "Wellcome Trust"
More from this funder
Funding agency for:
Kelly, C
+ "Wellcome Trust UK", "Oxford NIHR Biomedical Research Centre", "James Martin School for 21st Century"
More from this funder
Funding agency for:
Klenerman, P
Grant:
NIH V19A1082630
+ "Medical Research Council UK", "Oxford NIHR Biomedical Research Centre"
More from this funder
Funding agency for:
Barnes, E
Bibliographic Details
- Publisher:
- BMJ Publishing Group Publisher's website
- Journal:
- Gut Journal website
- Volume:
- 60
- Issue:
- 9
- Pages:
- 1284-1293
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1468-3288
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:86558d88-2334-4d13-b8e0-9f97d5bc90b2
- Local pid:
- ora:5939
- Deposit date:
- 2011-11-30
Related Items
Terms of use
- Copyright holder:
- C Kelly, P Klenerman & E Barnes
- Copyright date:
- 2011
- Notes:
- This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.
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