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Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium.

Abstract:

Candidate variant association studies have been largely unsuccessful in identifying common breast cancer susceptibility variants, although most studies have been underpowered to detect associations of a realistic magnitude. We assessed 41 common non-synonymous single-nucleotide polymorphisms (nsSNPs) for which evidence of association with breast cancer risk had been previously reported. Case-control data were combined from 38 studies of white European women (46 450 cases and 42 600 controls) ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddu311

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Journal:
Human molecular genetics
Volume:
23
Issue:
22
Pages:
6096-6111
Publication date:
2014-11-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:85a0ffeb-8d9f-4970-9ae5-9b6366dc1fee
Source identifiers:
470899
Local pid:
pubs:470899

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