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Leukoaraiosis, intracerebral hemorrhage, and functional outcome after acute stroke thrombolysis

Abstract:

To perform a systematic review and pooled meta-analysis of published studies to assess whether the presence of leukoaraiosis on neuroimaging before treatment with thrombolysis (IV or intra-arterial) is associated with an increased risk of symptomatic intracerebral hemorrhage (sICH) or poor functional outcome.We included studies of patients with acute ischemic stroke, treated with IV or intra-arterial thrombolysis, which assessed functional outcome (3-month modified Rankin Scale [mRS]) or sICH...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1212/wnl.0000000000003605

Authors


Kongbunkiat, K More by this author
Kasemsap, N More by this author
Tiamkao, S More by this author
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Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Neurology Journal website
Volume:
88
Issue:
7
Pages:
638-645
Publication date:
2017-01-27
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Pubs id:
pubs:679462
URN:
uri:8585e04a-363c-4b6e-bbdb-74a203163d4a
UUID:
uuid:8585e04a-363c-4b6e-bbdb-74a203163d4a
Local pid:
pubs:679462

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