Journal article
Evidence for the role of His-142 of protein 1C in the acid-induced disassembly of foot-and-mouth disease virus capsids.
- Abstract:
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Foot-and-mouth disease virus (FMDV) capsids are inherently labile under mildly acidic conditions, dissociating to pentamers at pH values in the region of 6.5, with the release of protein 1A and the viral RNA. This acid-induced disassembly is thought to be required for the entry of the virus genome into the host cell. Previous work has highlighted a histidine-alpha-helix charge-dipole interaction at the twofold axes of symmetry between pentamers and has suggested that this interaction plays a ...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of general virology More from this journal
- Volume:
- 80 ( Pt 8)
- Issue:
- 8
- Pages:
- 1911-1918
- Publication date:
- 1999-08-01
- EISSN:
-
1465-2099
- ISSN:
-
0022-1317
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:28324
- UUID:
-
uuid:852fbf47-cb27-4c76-8adf-0683d1fdd861
- Local pid:
-
pubs:28324
- Source identifiers:
-
28324
- Deposit date:
-
2012-12-19
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- Copyright date:
- 1999
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