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Journal article

Local exchange of metabolites shapes immunity

Abstract:

Immune cell differentiation and function depend on metabolic changes for the provision of energy and metabolites. Consequently, cellular metabolism relies on the availability of micronutrients such as vitamins and energy‐rich sources including amino acids and fatty acids. The bone marrow controls the continuous production of blood cells and is thereby reliant on the sophisticated interplay of progenitor and mature immune cells with its stromal microenvironment. The significance of stromal sub...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1111/imm.12978

Authors


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Institution:
University of Oxford
Division:
Medical Sciences
Department:
Pathology Dunn School
Oxford college:
St Hilda's College
Role:
Author
ORCID:
0000-0002-3415-3449
More by this author
Institution:
University of Oxford
Division:
Medical Sciences
Department:
Kennedy Institute of Rheumatology
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0002-4077-7995
Publisher:
John Wiley & Sons, Ltd. Publisher's website
Journal:
Immunology Journal website
Volume:
155
Issue:
3
Pages:
309-319
Publication date:
2018-07-04
Acceptance date:
2018-06-28
DOI:
EISSN:
1365-2567
ISSN:
0019-2805
Pubs id:
pubs:869360
URN:
uri:84e045a3-f783-4618-94ad-9f5cc11f8187
UUID:
uuid:84e045a3-f783-4618-94ad-9f5cc11f8187
Local pid:
pubs:869360

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