Journal article
Small heat-shock proteins: paramedics of the cell.
- Abstract:
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The small heat-shock proteins (sHSPs) comprise a family of molecular chaperones which are widespread but poorly understood. Despite considerable effort, comparatively few high-resolution structures have been determined for the sHSPs, a likely consequence of their tendency to populate ensembles of inter-converting conformational and oligomeric states at equilibrium. This dynamic structure appears to underpin the sHSPs' ability to bind and sequester target proteins rapidly, and renders them the...
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- Publisher copy:
- 10.1007/128_2012_324
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Authors
Bibliographic Details
- Journal:
- Topics in current chemistry
- Volume:
- 328
- Pages:
- 69-98
- Publication date:
- 2013-01-01
- DOI:
- EISSN:
-
1436-5049
- ISSN:
-
0340-1022
- Source identifiers:
-
329170
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:329170
- UUID:
-
uuid:846a1757-2416-4a70-8e68-789847367632
- Local pid:
- pubs:329170
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2013
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