Diagnosis of scrub typhus.

Journal article

Abstract:: Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and outline recommendations for future study.

Journal:: American journal of tropical medicine and hygiene More from this journal
Volume:: 82
Issue:: 3
Pages:: 368-370
Publication date:: 2010-03-01
DOI:: 10.4269/ajtmh.2010.09-0233
EISSN:: 1476-1645
ISSN:: 0002-9637

Language:: English
Keywords:: Humans

Fluorescent Antibody Technique, Indirect

Genetic Techniques

Scrub Typhus

Antigens, Bacterial

Immunoassay
Pubs id:: pubs:50307
UUID:: uuid:8461e2e2-c734-49ce-b8ce-5e59efdd0f71
Local pid:: pubs:50307
Source identifiers:: 50307
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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