Journal article
Targeted activation of cholinergic interneurons accounts for the modulation of dopamine by striatal nicotinic receptors
- Abstract:
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Striatal dopamine (DA) is a major player in action selection and reinforcement. DA release is under strong local control by striatal ACh acting at axonal nicotinic ACh receptors (nAChRs) on DA axons. Striatal nAChRs have been shown to control how DA is released in response to ascending activity from DA neurons, and they also directly drive DA release following synchronized activity in a small local cholinergic network. The source of striatal ACh has been thought to arise solely from intrinsic...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 891.3KB, Terms of use)
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- Publisher copy:
- 10.1523/ENEURO.0397-17.2018
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Bibliographic Details
- Publisher:
- Society for Neuroscience
- Journal:
- eNeuro More from this journal
- Volume:
- 5
- Issue:
- 5
- Article number:
- e0397
- Publication date:
- 2018-10-12
- Acceptance date:
- 2018-09-16
- DOI:
- EISSN:
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2373-2822
Item Description
- Keywords:
- Pubs id:
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pubs:924532
- UUID:
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uuid:836a3380-7a54-4e5e-9736-83aa86ea47b1
- Local pid:
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pubs:924532
- Source identifiers:
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924532
- Deposit date:
-
2018-10-08
Terms of use
- Copyright holder:
- Brimblecombe et al
- Copyright date:
- 2018
- Notes:
- © 2018 Brimblecombe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
- Licence:
- CC Attribution (CC BY)
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