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Antimicrobial resistance determinants are associated with Staphylococcus aureus bacteraemia and adaptation to the healthcare environment: a bacterial genome-wide association study

Abstract:

Staphylococcus aureus is a major bacterial pathogen in humans, and a dominant cause of severe bloodstream infections. Globally, antimicrobial resistance (AMR) in S. aureus remains challenging. While human risk factors for infection have been defined, contradictory evidence exists for the role of bacterial genomic variation in S. aureus disease. To investigate the contribution of bacterial lineage and genomic variation to the development of bloodstream infection, we undertook a genome-wide ass...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1099/mgen.0.000700

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Strategic
Role:
Author
Publisher:
Microbiology Society Publisher's website
Journal:
Microbial Genomics Journal website
Volume:
7
Issue:
11
Article number:
000700
Publication date:
2021-11-23
Acceptance date:
2021-09-30
DOI:
EISSN:
2057-5858
Language:
English
Keywords:
Pubs id:
1197252
Local pid:
pubs:1197252
Deposit date:
2021-10-01

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