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Cell-mediated immune response in vitro. II. The role of thymus and thymus-derived lymphocytes.

Abstract:

A recently developed allograft system for the generation of a cell-mediated response in tissue culture was applied to an analysis of the cells involved in that response. Lymphoid cells from CBA mice (H-2k) were immunized in vitro with mitomycin-treated BALB/c (H-2d) spleen cells and the cell-mediated response measured by lysis of 51Cr-labeled P815 mastocytoma cells (H-2d). It was found that in mouse spleen the precursor of cytotoxic lymphocytes, as well as the effector cells themselves are θ ...

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Cellular immunology
Volume:
4
Issue:
1
Pages:
39-50
Publication date:
1972-05-05
DOI:
EISSN:
1090-2163
ISSN:
0008-8749
URN:
uuid:82ce3db9-4f99-4484-9c67-a78175851255
Source identifiers:
482227
Local pid:
pubs:482227

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