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Sensitivity to bee and wasp venoms: association with specific IgE responses to the bee and wasp venom and HLA DRB1 and DPB1.

Abstract:

BACKGROUND: Stings from bees and wasps can cause systemic reactions which can be fatal in some individuals. In these venom-sensitive patients, specific IgE to the venom is produced and is considered to participate in the adverse reactions. This immune response requires antigen presentation by human leucocyte antigens (HLA) class II molecules, which includes DR and DP, which are present on antigen presenting cells. OBJECTIVE: To test for associations between HLA class II DRB1 and DPB1 alleles ...

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Publication status:
Published

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Authors


Moffatt, MF More by this author
Lalvani, A More by this author
Warrell, DA More by this author
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Journal:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume:
27
Issue:
5
Pages:
578-583
Publication date:
1997-05-05
DOI:
EISSN:
1365-2222
ISSN:
0954-7894
URN:
uuid:82c5712a-773b-4fb5-8358-07969d4c4c86
Source identifiers:
61204
Local pid:
pubs:61204

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