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Assessing the interruption of the transmission of human helminths with mass drug administration alone: optimizing the design of cluster randomized trials.

Abstract:

Background

A method is outlined for the use of an individual-based stochastic model of parasite transmission dynamics to assess different designs for a cluster randomized trial in which mass drug administration (MDA) is employed in attempts to eliminate the transmission of soil-transmitted helminths (STH) in defined geographic locations. The hypothesis to be tested is: Can MDA alone interrupt the transmission of STH species in defined settings? Clustering is at a village level an...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13071-017-1979-x

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-8428-3874
Publisher:
BioMed Central
Journal:
Parasites & Vectors More from this journal
Volume:
10
Issue:
1
Pages:
93
Publication date:
2017-02-01
Acceptance date:
2017-01-10
DOI:
EISSN:
1756-3305
ISSN:
1756-3305
Pmid:
28212667

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