- Abstract:
-
The effect of intravenous infusion of islet amyloid polypeptide (IAPP/amylin) and calcitonin gene-related peptide (CGRP) on blood glucose and plasma insulin in the basal and glucose-stimulated state was investigated in the anaesthetized rat. Both peptides had no effect on basal blood glucose or plasma insulin but following an intravenous bolus of glucose, CGRP-treated rats were hyperglycaemic and hyperinsulinaemic compared with control animals which were similar to IAPP-treated rats. IAPP had...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/bf01117233
-
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- Journal:
- Bioscience reports
- Volume:
- 10
- Issue:
- 4
- Pages:
- 339-345
- Publication date:
- 1990-08-05
- DOI:
- EISSN:
-
1573-4935
- ISSN:
-
0144-8463
- URN:
-
uuid:822762f0-9719-4927-b563-8d40c3521161
- Source identifiers:
-
72832
- Local pid:
- pubs:72832
- Copyright date:
- 1990
Journal article
The effect of islet amyloid polypeptide (amylin) and calcitonin gene-related peptide on glucose removal in the anaesthetized rat and on insulin secretion from rat pancreatic islets in vitro.
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