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Ultrafast search of all deposited bacterial and viral genomic data

Abstract:

Exponentially increasing amounts of unprocessed bacterial and viral genomic sequence data are stored in the global archives. The ability to query these data for sequence search terms would facilitate both basic research and applications such as real-time genomic epidemiology and surveillance. However, this is not possible with current methods. To solve this problem, we combine knowledge of microbial population genomics with computational methods devised for web search to produce a searchable ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41587-018-0010-1

Authors


Bradley, P More by this author
Den Bakker, HC More by this author
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ORCID:
0000-0001-7704-822X
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
BDI-NDM
Oxford college:
Linacre College
ORCID:
0000-0002-5012-4162
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ORCID:
0000-0001-8466-7547
More from this funder
Funding agency for:
McVean, G
Publisher:
Nature Publisher's website
Journal:
Nature Biotechnology Journal website
Volume:
37
Issue:
2
Pages:
152-159
Publication date:
2019-02-04
Acceptance date:
2018-12-20
DOI:
EISSN:
1546-1696
ISSN:
1087-0156
Pubs id:
pubs:969536
URN:
uri:822271d1-e5f6-4397-950d-476b6836ccd4
UUID:
uuid:822271d1-e5f6-4397-950d-476b6836ccd4
Local pid:
pubs:969536

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