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Journal article

Stage-specific promoter activity from stably maintained episomes in Plasmodium falciparum.

Abstract:

Genomic DNA is organised at its simplest level within phased arrays of nucleosomes, a structure key to the correct transcriptional regulation of the encoded genes. Here we studied chromatin formation on DNA transfected into Plasmodium falciparum either as an episomal plasmid or following integration by homologous recombination. We show that stably maintained and replicated plasmid assembles phased arrays of nucleosomes and that a reporter gene is transcribed in an appropriate temporal manner....

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Publication status:
Published

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Authors


Horrocks, P More by this author
Pinches, R More by this author
Newbold, C More by this author
Journal:
International journal for parasitology
Volume:
32
Issue:
10
Pages:
1203-1206
Publication date:
2002-09-05
DOI:
EISSN:
1879-0135
ISSN:
0020-7519
URN:
uuid:81aab5d6-08ec-4b89-bc0f-04e23b8230d9
Source identifiers:
94862
Local pid:
pubs:94862

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