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Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis

Abstract:

Background: Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal dosing regimen remains unclear. We undertook a systematic review and individual patient data meta-analysis to investigate the efficacy and tolerability of different primaquine dosing regimens to prevent P vivax recurrence.

Methods: For this systematic review and individual patient data meta-analysis, we searched MEDLINE, Web of Science, Embase, and Cochrane Ce...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s1473-3099(23)00430-9

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Publisher:
Elsevier
Journal:
Lancet Infectious Diseases More from this journal
Volume:
24
Issue:
2
Pages:
172-183
Publication date:
2023-09-22
DOI:
EISSN:
1474-4457
ISSN:
1473-3099


Language:
English
Keywords:
Pubs id:
1536407
Local pid:
pubs:1536407
Deposit date:
2023-09-26

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