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Monitoring digoxin therapy: I. Plasma concentrations and an in vitro assay of tissue response.

Abstract:
1 An in vitro technique is described for measuring the uptake of 86Rb by human erythrocytes. 2 Fifteen patients were treated with digoxin for atrial fibrillation and other fast arrhythmias. 3 86Rb uptake by the patients' own red cells fell from pre-treatment values during digitalization. 4 The therapeutic response of patients with atrial fibrillation correlated better with the changes in 86Rb uptake than with plasma digoxin concentrations.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-Seniors
Role:
Author
Journal:
British journal of clinical pharmacology
Volume:
4
Issue:
2
Pages:
213-221
Publication date:
1977-04-05
DOI:
EISSN:
1365-2125
ISSN:
0306-5251
URN:
uuid:81586b38-1166-400b-a5f1-a8b132084d5a
Source identifiers:
322129
Local pid:
pubs:322129

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