Journal article
A solution to the 2-pyridyl organometallic cross-coupling problem: regioselective catalytic direct arylation of pyridine N-oxides.
- Abstract:
- Direct arylation reactions of pyridine N-oxides occur in excellent yield with complete selectivity for the 2-position with a wide range of aryl bromides. This reactivity permits the use of inexpensive, commercially available, and bench-stable pyridine N-oxides as replacements for problematic 2-metallapyridines in palladium-catalyzed cross-coupling reactions.
- Publication status:
- Published
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- Publisher copy:
- 10.1021/ja056800x
Authors
- Journal:
- Journal of the American Chemical Society More from this journal
- Volume:
- 127
- Issue:
- 51
- Pages:
- 18020-18021
- Publication date:
- 2005-12-01
- DOI:
- EISSN:
-
1520-5126
- ISSN:
-
0002-7863
- Language:
-
English
- Pubs id:
-
pubs:416031
- UUID:
-
uuid:811e188a-1b13-4889-9e59-21c6a5eba322
- Local pid:
-
pubs:416031
- Source identifiers:
-
416031
- Deposit date:
-
2013-11-16
- ARK identifier:
Terms of use
- Copyright date:
- 2005
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