Modelling the effects of cardiac pulsations in arterial spin labelling.

Journal article

It has recently been demonstrated experimentally that cardiac pulsations seem significantly to affect the arterial spin labelling (ASL) signal. In this paper, we introduce a new theoretical model to examine this effect. Existing models of ASL do not take such effects into account since they model the transit of the ASL signal assuming uniform plug flow with a single transit delay. In this study, we model cardiac pulsations through the coupling of the Navier-Stokes equations with the three-dim...

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Authors: Kazan, S; Chappell, M; Payne, S

• Publication status: Published
• Journal: Physics in medicine and biology
• Volume: 55
• Issue: 3
• Pages: 799-816
• Publication date: 2010-02-01
• DOI: 10.1088/0031-9155/55/3/017
• EISSN: 1361-6560
• ISSN: 0031-9155
• Language: English
• Keywords: Models, Biological; Humans; Arteries; Blood Flow Velocity; Algorithms; Movement; Heart; Carotid Arteries; Diagnostic Imaging; Periodicity; Spin Labels; Regional Blood Flow