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Journal article

The La-related proteins, a family with connections to cancer

Abstract:

The evolutionarily-conserved La-related protein (LARP) family currently comprises Genuine La, LARP1, LARP1b, LARP4, LARP4b, LARP6 and LARP7. Emerging evidence suggests each LARP has a distinct role in transcription and/or mRNA translation that is attributable to subtle sequence variations within their La modules and specific C-terminal domains. As emerging research uncovers the function of each LARP, it is evident that La, LARP1, LARP6, LARP7 and possibly LARP4a and 4b are dysregulated in can...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3390/biom5042701

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Stavraka, C More by this author
Experimental Cancer Medicine Centres More from this funder
Cancer Research UK More from this funder
NIHR Biomedical Research Centre More from this funder
Publisher:
MDPI Publisher's website
Journal:
Biomolecules Journal website
Volume:
5
Issue:
4
Pages:
2701-2722
Publication date:
2015
DOI:
ISSN:
2218-273X
URN:
uuid:80fef12b-f77a-4ea0-ad63-5f3f7faad94f
Source identifiers:
571172
Local pid:
pubs:571172

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