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Prostate-specific antigen and related isoforms in the diagnosis and management of prostate cancer.

Abstract:

Despite its unparalleled merits for prostate cancer detection and staging, prostate-specific antigen (PSA) is not a marker for prostate cancer only, but also is expressed in benign conditions. For early detection, limitations of PSA are obvious. Its widespread use has led to an extensive amount of expensive and often unnecessary diagnostic procedures associated with significant morbidity. Total PSA derivatives may enhance the accuracy of prostate cancer diagnosis. The ratio of free-to-total P...

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Publisher copy:
10.1007/s11934-004-0042-6

Authors


Graefen, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
Current urology reports
Volume:
5
Issue:
3
Pages:
231-240
Publication date:
2004-06-05
DOI:
EISSN:
1534-6285
ISSN:
1527-2737
URN:
uuid:80fac277-0de1-4efb-87df-fbc5f49dc0e4
Source identifiers:
365986
Local pid:
pubs:365986

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