Journal article
TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis
- Abstract:
- This paper reports guidelines for the content of statistical analysis plans for early phase clinical trials, ensuring specification of the minimum reporting analysis requirements, by detailing extensions (11 new items) and modifications (25 items) to existing guidance after a review by various stakeholders
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.5MB, Terms of use)
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- Publisher copy:
- 10.1186/s13063-021-05384-5
Authors
+ Medical Research Council
More from this funder
- Funder identifier:
- 10.13039/501100000265
- Grant:
- MR/L005123/1
- Publisher:
- BioMed Central
- Journal:
- Trials More from this journal
- Volume:
- 22
- Issue:
- 1
- Pages:
- 433-433
- Article number:
- 433
- Publication date:
- 2021-07-06
- DOI:
- EISSN:
-
1745-6215
- ISSN:
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1745-6215
- Language:
-
English
- Keywords:
- Pubs id:
-
1186591
- Local pid:
-
pubs:1186591
- Source identifiers:
-
W3181942203
- Deposit date:
-
2026-03-25
- ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.
Terms of use
- Copyright date:
- 2021
- Licence:
- CC Attribution (CC BY)
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