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Journal article

Investigation of single-drug-encapsulating liposomes using the nano-impact method.

Abstract:
Encapsulating liposomes are widely used for controlled drug delivery. We report the use of nano-impact experiments for the electrochemical attomolar quantification of the liposome load, uniquely at the single liposome level, using vitamin C encapsulated liposomes as a model. The size of the liposomes and their picomolar concentration are also determined in biological buffer in real time.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/anie.201408934

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Role:
Author


Journal:
Angewandte Chemie International Edition More from this journal
Volume:
53
Issue:
50
Pages:
13928-13930
Publication date:
2014-12-01
DOI:
EISSN:
1521-3773
ISSN:
1433-7851


Language:
English
Keywords:
Pubs id:
pubs:486597
UUID:
uuid:80045a12-57b2-4bb6-a33c-552e6c3adeff
Local pid:
pubs:486597
Source identifiers:
486597
Deposit date:
2014-10-16

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