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Fixing the stimulus-as-fixed-effect fallacy in task fMRI

Abstract:

Most functional magnetic resonance imaging (fMRI) experiments record the brain's responses to samples of stimulus materials (e.g., faces or words). Yet the statistical modeling approaches used in fMRI research universally fail to model stimulus variability in a manner that affords population generalization, meaning that researchers' conclusions technically apply only to the precise stimuli used in each study, and cannot be generalized to new stimuli. A direct consequence of this stimulus-as-f...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.12688/wellcomeopenres.10298.2

Authors


Westfall, J More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
ORCID:
0000-0002-4516-5103
Yarkoni, T More by this author
Publisher:
Wellcome Trust Publisher's website
Journal:
Wellcome Open Research Journal website
Volume:
1
Pages:
23
Publication date:
2017-03-17
Acceptance date:
2016-12-09
DOI:
EISSN:
2398-502X
Pubs id:
pubs:896198
URN:
uri:7ff7bd1d-cd5f-4517-813c-48d059a95ed3
UUID:
uuid:7ff7bd1d-cd5f-4517-813c-48d059a95ed3
Local pid:
pubs:896198

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