Journal article icon

Journal article

Why clinical trial outcomes fail to translate into benefits for patients.

Abstract:

Clinical research should ultimately improve patient care. For this to be possible, trials must evaluate outcomes that genuinely reflect real-world settings and concerns. However, many trials continue to measure and report outcomes that fall short of this clear requirement. We highlight problems with trial outcomes that make evidence difficult or impossible to interpret and that undermine the translation of research into practice and policy. These complex issues include the use of surrogate, c...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1186/s13063-017-1870-2

Authors


More by this author
Department:
Kellogg College
More by this author
Department:
Oxford, MSD, Primary Care Health Sciences
More by this author
Department:
Oxford, MSD, Primary Care Health Sciences
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
18
Issue:
1
Pages:
122
Publication date:
2017-03-05
Acceptance date:
2017-02-28
DOI:
ISSN:
1745-6215
Pubs id:
pubs:686108
URN:
uri:7fd17c1d-597e-4e52-80da-5286bbdbb393
UUID:
uuid:7fd17c1d-597e-4e52-80da-5286bbdbb393
Local pid:
pubs:686108

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP