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Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome.

Abstract:

Juvenile polyposis syndrome (JPS; MIM 174900) is an autosomal dominant condition with incomplete penetrance characterized by hamartomatous polyps of the gastrointestinal tract and a risk of gastrointestinal cancer. Gastrointestinal hamartomatous polyps are also present in Cowden syndrome (CS; MIM 158350) and Bannayan-Zonana syndrome (BZS; also called Ruvalcaba-Myhre-Smith syndrome; MIM 153480). The susceptibility locus for both CS and BZS has recently been identified as the novel tumor suppre...

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Publication status:
Published

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Authors


Lunetta, KL More by this author
Hemminki, A More by this author
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Journal:
Cancer research
Volume:
57
Issue:
22
Pages:
5017-5021
Publication date:
1997-11-05
EISSN:
1538-7445
ISSN:
0008-5472
URN:
uuid:7fb95a31-6c83-410e-a078-ec3e22d83daa
Source identifiers:
72330
Local pid:
pubs:72330

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