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Journal article

Moderate hypothermia to treat perinatal asphyxial encephalopathy.

Abstract:

BACKGROUND: Whether hypothermic therapy improves neurodevelopmental outcomes in newborn infants with asphyxial encephalopathy is uncertain. METHODS: We performed a randomized trial of infants who were less than 6 hours of age and had a gestational age of at least 36 weeks and perinatal asphyxial encephalopathy. We compared intensive care plus cooling of the body to 33.5 degrees C for 72 hours and intensive care alone. The primary outcome was death or severe disability at 18 months of age. Pre...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1056/nejmoa0900854

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
Publisher:
Massachusetts Medical Society
Journal:
New England journal of medicine More from this journal
Volume:
361
Issue:
14
Pages:
1349-1358
Publication date:
2009-10-01
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Language:
English
Keywords:
Pubs id:
pubs:236854
UUID:
uuid:7fb19cea-f15c-41eb-8893-0695934ab7a7
Local pid:
pubs:236854
Source identifiers:
236854
Deposit date:
2012-12-19

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