Journal article

Generalised urticaria and angioedema complicating switch back from subcutaneous to intravenous vedolizumab therapy

Abstract:: We report a unique case of a 34-year-old man with ulcerative colitis, previously in complete remission with intravenous vedolizumab monotherapy, who developed an urticarial injection-site reaction on switching to a subcutaneous preparation and thereafter experienced a new hypersensitivity reaction on switch back to intravenous vedolizumab, necessitating complete discontinuation from this drug. This case highlights the need for vigilance on switching back to intravenous preparations of vedolizumab, in response to injection-site reactions with a subcutaneous preparation, even if the intravenous preparation had been previously well tolerated by the patient.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Chauhan, D., Prabhu, A., Cripps, S., Misbah, S., Griffiths, K., Roseman, A., Walsh, A., & Satsangi, J. (2023). Generalised urticaria and angioedema complicating switch back from subcutaneous to intravenous vedolizumab therapy. Frontline Gastroenterology, 14(5), 432–434.

MLA Style

Chauhan, D, et al. “Generalised Urticaria and Angioedema Complicating Switch Back from Subcutaneous to Intravenous Vedolizumab Therapy.” Frontline Gastroenterology, vol. 14, no. 5, 2023, pp. 432–34.

Chicago Style

Chauhan, D, A Prabhu, S Cripps, et al. 2023. “Generalised Urticaria and Angioedema Complicating Switch Back from Subcutaneous to Intravenous Vedolizumab Therapy.” Frontline Gastroenterology 14 (5): 432–34.
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Publisher copy:: 10.1136/flgastro-2023-102380

Authors

+ Chauhan, D More by this author

Role:: Author

+ Prabhu, A More by this author

Role:: Author

+ Cripps, S More by this author

Role:: Author

+ Misbah, S More by this author

Role:: Author

+ Griffiths, K More by this author

Role:: Author

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Publisher:: BMJ Publishing Group
Journal:: Frontline Gastroenterology More from this journal
Volume:: 14
Issue:: 5
Pages:: 432-434
Place of publication:: England
Publication date:: 2023-03-27
Acceptance date:: 2023-03-17
DOI:: 10.1136/flgastro-2023-102380
EISSN:: 2041-4145
ISSN:: 2041-4137
Pmid:: 37581188

Language:: English
Pubs id:: 1541066
UUID:: uuid_7fb11933-24bd-4fed-b993-aeb8a49ec275
Local pid:: pubs:1541066
Source identifiers:: W4361017980
Deposit date:: 2026-01-23
ARK identifier:: ark:/29072/ora_7fb1193324bd4fedb993aeb8a49ec275

Terms of use

Copyright holder:: Chauhan et al
Copyright date:: 2023
Rights statement:: © Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Licence:: Other

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