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Alverine citrate fails to relieve the symptoms of irritable bowel syndrome: Results of a double-blind, randomized, placebo-controlled trial

Abstract:

Background: Alverine citrate has been used in the treatment of irritable bowel syndrome for many years. Aims: To compare the efficacy and safety of a new formulation of alverine citrate, a 120-mg capsule, with placebo given three times daily for 12 weeks. Methods: One hundred and seven patients with irritable bowel syndrome were entered into this three-centre, double-blind, randomized, placebo-controlled, parallel group trial. The primary end-point was relief of abdominal pain indicated by im...

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Journal:
Alimentary Pharmacology and Therapeutics
Volume:
16
Issue:
6
Pages:
1187-1195
Publication date:
2002-01-01
DOI:
ISSN:
0269-2813
URN:
uuid:7f420081-1d3e-417c-ae89-7a3b7070b2c1
Source identifiers:
171750
Local pid:
pubs:171750
Language:
English

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