Journal article
Identification and characterization of in vivo attenuated mutants of Brucella melitensis.
- Abstract:
-
Brucella melitensis 16M is a Gram-negative alpha2-proteobacterium responsible for abortion in goats and for Malta fever in humans. This facultative intracellular pathogen invades into and survives within both professional and non-professional phagocytes. Signature-tagged mutagenesis (STM) was used to identify genes required for the in vivo pathogenesis of Brucella. A library of transposon mutants was screened in a murine infection model. Out of 672 mutants screened, 20 were not recovered afte...
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- Publisher copy:
- 10.1046/j.1365-2958.2000.02150.x
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Authors
Bibliographic Details
- Journal:
- Molecular microbiology
- Volume:
- 38
- Issue:
- 3
- Pages:
- 543-551
- Publication date:
- 2000-11-05
- DOI:
- EISSN:
-
1365-2958
- ISSN:
-
0950-382X
- URN:
-
uuid:7ebe70b5-fea3-427d-b73e-0741c0806930
- Source identifiers:
-
246341
- Local pid:
- pubs:246341
Item Description
Terms of use
- Copyright date:
- 2000
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