- Abstract:
-
In this study, bovine articular and human chondrocytes from the C-20/A4 cell line were tested for the functional activity and molecular presence of the enzyme carbonic anhydrase. This enzyme is classically considered to be important in the maintenance of high cellular buffering capacity by catalysing the slow attainment of equilibrium between CO(2) and HCO(3)(-). The first functional assay measured the rate of pH equilibration after administration of a fixed dose of CO(2) solution to cell lys...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s1096-4959(02)00184-7
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- Journal:
- Comparative biochemistry and physiology. Part B, Biochemistry and molecular biology
- Volume:
- 133
- Issue:
- 3
- Pages:
- 427-435
- Publication date:
- 2002-11-05
- DOI:
- EISSN:
-
1879-1107
- ISSN:
-
1096-4959
- URN:
-
uuid:7e92dd0e-fbe4-4803-907d-a07072acf3fd
- Source identifiers:
-
113760
- Local pid:
- pubs:113760
- Copyright date:
- 2002
Journal article
Functional and molecular determination of carbonic anhydrase levels in bovine and cultured human chondrocytes.
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