Journal article

Synthesis of anthraquinone oligonucleotides for triplex stabilization.

Abstract:: The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.

Publication status:: Published

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APA Style

Zhao, Z., Peng, G., Michels, J., Fox, K., & Brown, T. (2007). Synthesis of anthraquinone oligonucleotides for triplex stabilization. Nucleosides, Nucleotides and Nucleic Acids, 26(8-9), 921–925.

MLA Style

Zhao, Z., et al. “Synthesis of Anthraquinone Oligonucleotides for Triplex Stabilization.” Nucleosides, Nucleotides and Nucleic Acids, vol. 26, no. 8-9, 2007, pp. 921–25.

Chicago Style

Zhao, Z, G Peng, J Michels, K Fox, and T Brown. 2007. “Synthesis of Anthraquinone Oligonucleotides for Triplex Stabilization.” Nucleosides, Nucleotides and Nucleic Acids 26 (8-9): 921–25.
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Publisher copy:: 10.1080/15257770701506491

Authors

+ Zhao, Z More by this author

Role:: Author

+ Peng, G More by this author

Role:: Author

+ Michels, J More by this author

Role:: Author

+ Fox, K More by this author

Role:: Author

+ Brown, T More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

Journal:: Nucleosides, nucleotides and nucleic acids More from this journal
Volume:: 26
Issue:: 8-9
Pages:: 921-925
Publication date:: 2007-01-01
DOI:: 10.1080/15257770701506491
EISSN:: 1532-2335
ISSN:: 1525-7770

Language:: English
Keywords:: Fluorescence

Molecular Structure

Drug Stability

Nucleic Acid Conformation

Anthraquinones

Base Sequence

Oligodeoxyribonucleotides

Drug Design
Pubs id:: pubs:400022
UUID:: uuid:7e434d3c-7343-4d20-96fb-29a6ff5dd0d1
Local pid:: pubs:400022
Source identifiers:: 400022
Deposit date:: 2013-11-16

Terms of use

Copyright date:: 2007

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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