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CAMPATH-1H in inflammatory arthritis.

Abstract:
CAMPATH-1H is a humanised mAb directed against lymphocytes. This mAb has been used to treat patients with rheumatoid arthritis. Clinical improvement with reduction in the Ritchie index and joint score has lasted for up to 8 months in some patients. A profound and prolonged lymphopaenia is induced by the mAb, with CD4+ numbers remaining suppressed for up to one year.
Publication status:
Published

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Authors


Isaacs, JD More by this author
Hazleman, BL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Volume:
11 Suppl 8
Pages:
S165-S167
Publication date:
1993
ISSN:
0392-856X
URN:
uuid:7de70dc9-63dd-4b28-a640-5f87ee6d206c
Source identifiers:
28383
Local pid:
pubs:28383

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