Journal article
Total synthesis of antascomicin B.
- Abstract:
- (Chemical Equation Presented) The structurally enticing antascomicin B (1), which exhibits potent immunosuppressant-antagonizing properties, has a complex polyketide structure. Key steps in its enantioselective total synthesis include a transannular catechol-templated Dieckmann reaction to assemble the challenging tricarbonyl functionality and a butanediacetal-directed allylation. © 2005 Wiley-VCH Verlag GmbH and Co. KGaA.
- Publication status:
- Published
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Authors
- Journal:
- Angewandte Chemie (International ed. in English) More from this journal
- Volume:
- 44
- Issue:
- 18
- Pages:
- 2732-2737
- Publication date:
- 2005-04-01
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:58747
- UUID:
-
uuid:7c638b51-c3fb-4920-94b3-d5868bc5240b
- Local pid:
-
pubs:58747
- Source identifiers:
-
58747
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2005
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