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Thesis

MRI and histological analysis of brain metastasis and the effect of systemic inflammation

Abstract:

Background

Brain metastasis is a leading cause of cancer mortality and affects 20-40% of all cancer patients. The BBB is responsible for isolation and protection of the brain parenchyma from many diagnostic and therapeutic agents. New molecular agents that target tumour-associated VCAM-1 expression on the brain endothelium show improvements in the early diagnosis of brain metastasis. The vascular endothelium of the CNS plays an important role in the maintenance of t...

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Contributors

Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Research group:
Experimental Neuroimaging Group
Oxford college:
New College
Department:
Medical Sciences Division - Radiation,Oncology and Biology
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Funding agency for:
Alastair M A Hamilton
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:7bd5c6b9-592a-4afa-8053-907db849a0d9
Local pid:
ora:7321

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