Journal article
Considerations for the design, analysis and presentation of in vivo studies
- Abstract:
- Important statistical principles and key methodological challenges in the study design, statistical analysis, and reporting of results from in vivo studies are considered along with the underlying statistical principles and practical suggestions. The importance of pre-specifying endpoints and analysis, the common underlying assumption of statistically independent observations, sample size considerations, and multiplicity issues are considered. Additionally, the reporting of results and graphical presentations are also discussed.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 412.7KB, Terms of use)
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- Publisher copy:
- 10.1016/j.joca.2016.06.023
Authors
- Publisher:
- Elsevier
- Journal:
- Osteoarthritis and Cartilage More from this journal
- Volume:
- 25
- Issue:
- 3
- Pages:
- 364-368
- Publication date:
- 2016-07-30
- Acceptance date:
- 2016-06-28
- DOI:
- EISSN:
-
1522-9653
- ISSN:
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1063-4584
- Keywords:
- Pubs id:
-
pubs:633284
- UUID:
-
uuid:7b8ccb83-52e0-4b15-84e3-9a41205c318f
- Local pid:
-
pubs:633284
- Source identifiers:
-
633284
- Deposit date:
-
2016-07-13
- ARK identifier:
Terms of use
- Copyright holder:
- Osteoarthritis Research Society International
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.joca.2016.06.023
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