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Journal article

Considerations for the design, analysis and presentation of in vivo studies

Abstract:
Important statistical principles and key methodological challenges in the study design, statistical analysis, and reporting of results from in vivo studies are considered along with the underlying statistical principles and practical suggestions. The importance of pre-specifying endpoints and analysis, the common underlying assumption of statistically independent observations, sample size considerations, and multiplicity issues are considered. Additionally, the reporting of results and graphical presentations are also discussed.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.joca.2016.06.023

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, CSM
Ranstam, J More by this author
Publisher:
Elsevier Publisher's website
Journal:
Osteoarthritis and Cartilage Journal website
Volume:
25
Issue:
3
Pages:
364-368
Publication date:
2016-07-30
Acceptance date:
2016-06-28
DOI:
EISSN:
1522-9653
ISSN:
1063-4584
URN:
uuid:7b8ccb83-52e0-4b15-84e3-9a41205c318f
Source identifiers:
633284
Local pid:
pubs:633284

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