Journal article icon

Journal article

Abnormal oscillatory synchronisation in the motor system leads to impaired movement.

Abstract:

Converging data suggest that abnormal synchronised oscillatory activity in the basal ganglia may contribute to bradykinesia in patients with Parkinson's disease. This synchrony preferentially occurs over 10-30 Hz, the so-called beta band. Correlative evidence has been supplemented by experiments in which direct stimulation of the basal ganglia in the beta band slows movement. Yet questions remain regarding the small scale of the latter effects and whether synchrony is an early or even obligat...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.conb.2007.12.001

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Journal:
Current opinion in neurobiology
Volume:
17
Issue:
6
Pages:
656-664
Publication date:
2007-12-05
DOI:
EISSN:
1873-6882
ISSN:
0959-4388
URN:
uuid:7b84958e-faca-45ff-9e09-ad879d28c933
Source identifiers:
70897
Local pid:
pubs:70897

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP