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Journal article

Abnormal oscillatory synchronisation in the motor system leads to impaired movement.

Abstract:

Converging data suggest that abnormal synchronised oscillatory activity in the basal ganglia may contribute to bradykinesia in patients with Parkinson's disease. This synchrony preferentially occurs over 10-30 Hz, the so-called beta band. Correlative evidence has been supplemented by experiments in which direct stimulation of the basal ganglia in the beta band slows movement. Yet questions remain regarding the small scale of the latter effects and whether synchrony is an early or even obligat...

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Publication status:
Published

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Publisher copy:
10.1016/j.conb.2007.12.001

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
Journal:
Current opinion in neurobiology
Volume:
17
Issue:
6
Pages:
656-664
Publication date:
2007-12-01
DOI:
EISSN:
1873-6882
ISSN:
0959-4388
Source identifiers:
70897
Language:
English
Keywords:
Pubs id:
pubs:70897
UUID:
uuid:7b84958e-faca-45ff-9e09-ad879d28c933
Local pid:
pubs:70897
Deposit date:
2013-02-20

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