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Escalation and intensification of radiotherapy for stage III non-small cell lung cancer: opportunities for treatment improvement.

Abstract:

In this overview we review and model how radiotherapy tumour control and complication rates vary with dose, fractionation, schedule duration, irradiated volume and use of chemotherapy for stage III non-small cell lung cancer (NSCLC), and use the modelling to study the effectiveness of different NSCLC dose-escalation approaches being developed in the UK. Data have been collated for pneumonitis, lung fibrosis, early and late oesophagitis, cord and cardiac complications, and local progression-fr...

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Publication status:
Published

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Publisher copy:
10.1016/j.clon.2008.12.011

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Clinical oncology (Royal College of Radiologists (Great Britain))
Volume:
21
Issue:
4
Pages:
343-360
Publication date:
2009-05-01
DOI:
EISSN:
1433-2981
ISSN:
0936-6555
Source identifiers:
228634
Language:
English
Keywords:
Pubs id:
pubs:228634
UUID:
uuid:7b7cd207-32ec-4652-81ad-e5908391e19c
Local pid:
pubs:228634
Deposit date:
2012-12-19

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