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Rapid evolution and the importance of recombination to the gastroenteric pathogen Campylobacter jejuni.

Abstract:

Responsible for the majority of bacterial gastroenteritis in the developed world, Campylobacter jejuni is a pervasive pathogen of humans and animals, but its evolution is obscure. In this paper, we exploit contemporary genetic diversity and empirical evidence to piece together the evolutionary history of C. jejuni and quantify its evolutionary potential. Our combined population genetics-phylogenetics approach reveals a surprising picture. Campylobacter jejuni is a rapidly evolving species, su...

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Publication status:
Published

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Publisher copy:
10.1093/molbev/msn264

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Gabriel, E More by this author
Leatherbarrow, AJ More by this author
Cheesbrough, J More by this author
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Journal:
Molecular biology and evolution
Volume:
26
Issue:
2
Pages:
385-397
Publication date:
2009-02-05
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
URN:
uuid:7b782242-1e29-46cb-9917-b52d9e81cacc
Source identifiers:
69643
Local pid:
pubs:69643

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