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Rapid evolution and the importance of recombination to the gastroenteric pathogen Campylobacter jejuni.

Abstract:

Responsible for the majority of bacterial gastroenteritis in the developed world, Campylobacter jejuni is a pervasive pathogen of humans and animals, but its evolution is obscure. In this paper, we exploit contemporary genetic diversity and empirical evidence to piece together the evolutionary history of C. jejuni and quantify its evolutionary potential. Our combined population genetics-phylogenetics approach reveals a surprising picture. Campylobacter jejuni is a rapidly evolving species, su...

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Publication status:
Published

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Publisher copy:
10.1093/molbev/msn264

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Molecular biology and evolution
Volume:
26
Issue:
2
Pages:
385-397
Publication date:
2009-02-01
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
Source identifiers:
69643
Language:
English
Keywords:
Pubs id:
pubs:69643
UUID:
uuid:7b782242-1e29-46cb-9917-b52d9e81cacc
Local pid:
pubs:69643
Deposit date:
2012-12-19

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