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The Physiological and Pathological Implications of the Formation of Hydrogels, with a Specific Focus on Amyloid Polypeptides

Abstract:

Hydrogels are water-swollen and viscoelastic three-dimensional cross-linked polymeric network originating from monomer polymerisation. Hydrogel-forming polypeptides are widely found in nature and, at a cellular and organismal level, they provide a wide range of functions for the organism making them. Amyloid structures, arising from polypeptide aggregation, can be damaging or beneficial to different types of organisms. Although the best-known amyloids are those associated with human pathologi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3390/biom7040070

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Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Department:
Oxford, MSD, Pathology Dunn School
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Author
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Department:
Lincoln College
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Author
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Funding agency for:
Jean, L
Publisher:
MDPI Publisher's website
Journal:
Biomolecules Journal website
Volume:
7
Issue:
4
Pages:
1-35
Publication date:
2017-09-22
Acceptance date:
2017-09-17
DOI:
ISSN:
2218-273X
Pubs id:
pubs:729224
URN:
uri:7b4b2b90-35da-4baa-b9e2-e0c0695940dd
UUID:
uuid:7b4b2b90-35da-4baa-b9e2-e0c0695940dd
Local pid:
pubs:729224

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