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Journal article

Malignant pleural effusions: management options

Abstract:
Malignant pleural effusion (MPE) represents advanced metastatic malignancy and is associated with poor median survival. Incidence remains high and continues to rise, in part due to changing population demographics. This therefore represents a significant health care burden. Management is predominantly palliative in nature and multiple interventions are available within conventional treatment paradigms, all of which are proven to result in statistically significant patient benefit. This article further explores the methods available in the management of MPE along with the pitfalls, complications, and alternatives. Recent advances within the field are discussed with an exploration of likely future directions, including the role of ultrasound as a prospective predictor and the role of intrapleural fibrinolytic therapy.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1055/s-0038-1676572

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0003-1195-1680


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Grant:
MCCC-RP-14-A17178


Publisher:
Thieme Publishing
Journal:
Seminars in Respiratory and Critical Care Medicine More from this journal
Volume:
39
Issue:
6
Pages:
704-712
Publication date:
2019-01-14
Acceptance date:
2018-10-01
DOI:
EISSN:
1098-9048
ISSN:
1069-3424
Pmid:
30641588


Language:
English
Keywords:
Pubs id:
pubs:966051
UUID:
uuid:7afb0213-dfc9-48d3-9e76-61b082965a58
Local pid:
pubs:966051
Source identifiers:
966051
Deposit date:
2019-01-31

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