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Clinical and cost-effectiveness of two ways of delivering guided self-help for people with an eating disorder: A multi-arm randomized controlled trial

Abstract:
Objective Increasing the availability and accessibility of evidence-based treatments for eating disorders is an important goal. This study investigated the effectiveness and cost-effectiveness of guided self-help via face-to-face meetings (fGSH) and a more scalable method, providing support via email (eGSH).
Method A pragmatic, randomized controlled trial was conducted at three sites. Adults with binge-eating disorders were randomized to fGSH, eGSH, or a waiting list condition, each lasting 12 weeks. The primary outcome variable for clinical effectiveness was overall severity of eating psychopathology and, for cost-effectiveness, binge-free days, with explorative analyses using symptom abstinence. Costs were estimated from both a partial societal and healthcare provider perspective.
Results Sixty participants were included in each condition. Both forms of GSH were superior to the control condition in reducing eating psychopathology (IRR = −1.32 [95% CI −1.77, −0.87], p < .0001; IRR = −1.62 [95% CI −2.25, −1.00], p < .0001) and binge eating. Attrition was higher in eGSH. Probabilities that fGSH and eGSH were cost-effective compared with WL were 93% (99%) and 51% (79%), respectively, for a willingness to pay of £100 (£150) per additional binge-free day.
Discussion Both forms of GSH were associated with clinical improvement and were likely to be cost-effective compared with a waiting list condition. Provision of support via email is likely to be more convenient for many patients although the risk of non-completion is greater.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/eat.23554

Authors


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Role:
Author
ORCID:
0000-0003-1673-2903
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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author


Publisher:
Wiley
Journal:
International Journal of Eating Disorders More from this journal
Volume:
54
Issue:
7
Pages:
1224-1237
Publication date:
2021-05-17
Acceptance date:
2021-05-10
DOI:
EISSN:
1098-108X


Language:
English
Keywords:
Pubs id:
1178309
Local pid:
pubs:1178309
Deposit date:
2021-05-26

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