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Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assay.

Abstract:

Anti-angiogenic strategies are emerging as an important tool for the treatment of cancer and inflammatory diseases. In the present investigation we isolated several isoflavones from a tempeh (fermented soyabean) extract. The isolated isoflavones were identified as 5,7,4'-trihydroxyisoflavone (genistein), 7,4'-dihydroxyisoflavone (daidzein), 6,7,4'-trihydroxyisoflavone (factor 2), 7,8,4'-trihydroxyisoflavone (7,8,4'-TriOH) and 5,7,3',4'-tetrahydroxyisoflavone (orobol). The effects on angiogene...

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Publisher copy:
10.1079/bjn20041330

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Högemeier, O More by this author
Starcke, S More by this author
Dombrowski, F More by this author
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Journal:
The British journal of nutrition
Volume:
93
Issue:
3
Pages:
317-323
Publication date:
2005-03-05
DOI:
EISSN:
1475-2662
ISSN:
0007-1145
URN:
uuid:7a546960-ffd3-47f0-8d23-4df291b5847e
Source identifiers:
271204
Local pid:
pubs:271204

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