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Journal article

The reorganization and reactivation of hippocampal maps predict spatial memory performance.

Abstract:

The hippocampus is an important brain circuit for spatial memory and the spatially selective spiking of hippocampal neuronal assemblies is thought to provide a mnemonic representation of space. We found that remembering newly learnt goal locations required NMDA receptor-dependent stabilization and enhanced reactivation of goal-related hippocampal assemblies. During spatial learning, place-related firing patterns in the CA1, but not CA3, region of the rat hippocampus were reorganized to repres...

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Publication status:
Published

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Publisher copy:
10.1038/nn.2599

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Nature neuroscience
Volume:
13
Issue:
8
Pages:
995-1002
Publication date:
2010-08-01
DOI:
EISSN:
1546-1726
ISSN:
1097-6256
Source identifiers:
329229
Language:
English
Keywords:
UUID:
uuid:7a48c442-78c2-4a1a-b8ec-9845bd870c21
Local pid:
pubs:329229
Deposit date:
2013-11-16

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