Isolation and characterization of a two-coordinate phosphinidene oxide

Journal article

Nitroso compounds, R-N=O, are common intermediates in organic synthesis, and are typically amenable to storage and manipulation at ambient temperature under aerobic conditions. By contrast, phosphorus-containing analogues, such as R-P=O (R = OH, CH₃, OCH₃, Ph), are extremely reactive and need to be studied in inert gas matrices at ultralow temperatures (3-15 K). These species are believed to be key intermediates in the degradation/combustion of organic phosphorus compounds, a class of chemicals that includes chemical warfare agents and flame retardants. Here we describe the isolation of a two-coordinate phosphorus(III) oxide under ambient conditions, enabled by the use of an extremely bulky amine ligand. Reactivity studies reveal that the phosphorus centre can be readily oxidized, and that in doing so, the P-O bond remains intact, an observation that is of interest to the proposed reactivity of transient phosphorus(III) oxides.

Authors: Hu, C; Rees, NH; Pink, M; Goicoechea, JM

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Springer Nature
• Journal: Nature Chemistry
• Volume: 16
• Issue: 11
• Pages: 1855–1860
• Place of publication: England
• Publication date: 2024-07-15
• Acceptance date: 2024-06-21
• DOI: 10.1038/s41557-024-01586-x
• EISSN: 1755-4349
• ISSN: 1755-4330
• Pmid: 39009793
• Language: English