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Journal article

The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time daily: a 26-week, randomized, open-label, parallel-group, treat-to-target trial in individuals with type 2 diabetes.

Abstract:

OBJECTIVE: The requirement to inject current basal insulin analogs at a fixed time each day may complicate adherence and compromise glycemic control. This trial evaluated the efficacy and safety of varying the daily injection time of insulin degludec (IDeg), an ultra-long-acting basal insulin. RESEARCH DESIGN AND METHODS: This 26-week, open-label, treat-to-target trial enrolled adults (≥18 years) with type 2 diabetes who were either insulin naïve and receiving oral antidiabetic drugs (OADs) (...

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Publication status:
Published

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Publisher copy:
10.2337/dc12-1668

Authors


Meneghini, L More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
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Journal:
Diabetes care
Volume:
36
Issue:
4
Pages:
858-864
Publication date:
2013-04-05
DOI:
EISSN:
1935-5548
ISSN:
0149-5992
URN:
uuid:7a257276-1d99-4abf-ad68-92738873240c
Source identifiers:
395245
Local pid:
pubs:395245

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