Journal article
Time-dependent extracellular matrix alterations of young tendons in response to stress relaxation: a model for the Ponseti method
- Abstract:
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The Ponseti method corrects a clubfoot by manipulation and casting which causes stress relaxation on the tendons. Here, we examined the effect of long-term stress relaxation on tendon extracellular matrix (ECM) by (1) an ex vivo stress relaxation test, (2) an in vitro tenocyte culture with stress relaxation and (3) an in vivo rabbit study. Time-dependent tendon lengthening and ECM alterations including crimp angle reduction and cleaved elastin were observed, which illustrated the mechanism of...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 3.3MB, Terms of use)
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(Preview, Version of record, pdf, 936.0KB, Terms of use)
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- Publisher copy:
- 10.1098/rsif.2022.0712
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Funding
Bibliographic Details
- Publisher:
- Royal Society
- Journal:
- Journal of the Royal Society Interface More from this journal
- Volume:
- 20
- Issue:
- 202
- Article number:
- 20220712
- Publication date:
- 2023-05-17
- Acceptance date:
- 2023-04-06
- DOI:
- EISSN:
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1742-5662
- ISSN:
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1742-5662
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1339573
- Local pid:
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pubs:1339573
- Deposit date:
-
2023-05-03
Terms of use
- Copyright holder:
- Lee et al.
- Copyright date:
- 2023
- Rights statement:
- © 2023 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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