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A multicentre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and health-care resource use following cardiac surgery (TITRe2).

Abstract:
The study found that a restrictive transfusion threshold of red blood cells is not superior to a liberal threshold after cardiac surgery. This finding supports restrictive transfusion due to reduced consumption and costs of red blood cells. However, secondary findings create uncertainty about recommending restrictive transfusion and prompt a new hypothesis that liberal transfusion may be superior after cardiac surgery.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3310/hta20600

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author


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Grant:
Health Technology Assessment programme 06/402/94


Publisher:
NIHR Health Technology Assessment Programme
Journal:
Health Technology Assessment More from this journal
Volume:
20
Issue:
60
Pages:
1-260
Publication date:
2016-08-01
Acceptance date:
2015-01-16
DOI:
EISSN:
2046-4924
ISSN:
1366-5278
Pmid:
27527344


Language:
English
Keywords:
Pubs id:
pubs:639016
UUID:
uuid:7a0312af-17fa-4c10-96bb-00b82e6aeeae
Local pid:
pubs:639016
Deposit date:
2016-12-02
ARK identifier:

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