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Sulcogyral variation in NMDA receptor 2A/B subunit immunoreactivity in human brain.

Abstract:

NMDA receptors (NR) are important in many neurological processes. Using a large series of human brain tissue, we show that the distribution of NR2A/B immunoreactivity varies according to position along a gyrus. For pyramidal neurons in laminae II and III, immunoreactivity is most marked at gyral crown and gyral lips, diminishes along sulcal wall, and is barely detectable in sulcal floor cortex. In contrast, in some cases, immunoreactivity in laminae V and VI pyramidal neurons shows the revers...

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Publication status:
Published

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Authors


Sisodiya, SM More by this author
Heffernan, J More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Squier, MV More by this author
Journal:
Neuroreport
Volume:
11
Issue:
11
Pages:
2601-2606
Publication date:
2000-08-05
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
URN:
uuid:79f04b68-4d72-4aaa-b4f8-44f436123df3
Source identifiers:
98164
Local pid:
pubs:98164

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