Journal article icon

Journal article

The influence of recombination on human genetic diversity.

Abstract:

In humans, the rate of recombination, as measured on the megabase scale, is positively associated with the level of genetic variation, as measured at the genic scale. Despite considerable debate, it is not clear whether these factors are causally linked or, if they are, whether this is driven by the repeated action of adaptive evolution or molecular processes such as double-strand break formation and mismatch repair. We introduce three innovations to the analysis of recombination and diversit...

Expand abstract

Actions


Access Document


Authors


Spencer, CC More by this author
Deloukas, P More by this author
Mullikin, J More by this author
Expand authors...
Journal:
PLoS genetics
Volume:
2
Issue:
9
Publication date:
2006-09-22
DOI:
EISSN:
1553-7404
URN:
uuid:79e27d6e-0dcb-4fdf-9875-c1399ae57435
Source identifiers:
88666
Local pid:
pubs:88666
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP